The CIP online cleaning system is one of the prerequisites for hygiene standards in drug production. It can eliminate cross contamination of active ingredients, eliminate insoluble foreign particles, and reduce or eliminate contamination of drugs by microorganisms and heat sources. GMP requires that efforts be made to recommend the use of CIP online cleaning systems in the pharmaceutical industry. However, due to the high cost of CIP online cleaning systems abroad, their use by Chinese pharmaceutical enterprises is restricted. The professional technical personnel of Lihong Company have digested and absorbed the advanced foreign technology introduced in response to many problems, and successfully developed a CIP online cleaning system with advantages such as high automation, easy operation, and reasonable price.

Performance characteristics of CIP online cleaning system:

1. Not only can it clean the equipment, but it can also control microbial growth.

2. Compared with manual cleaning, it saves labor and improves drug quality.

3. Reduced cleaning costs, reduced consumption of cleaning agents, water, and steam

4. It can be operated automatically by remote control or PLC program control (optional).

The CIP online cleaning system refers to the equipment (tanks, pipelines, pumps, filters, etc.) and the entire production line that, without the need for manual disassembly or opening, sprays and circulates a certain temperature of cleaning solution on the surface of the equipment through a closed pipeline flow rate within a predetermined time to achieve the cleaning purpose, specifically known as the CIP online cleaning system. A stable CIP online cleaning system relies on excellent design. The company's professionals determine the appropriate cleaning process based on the actual situation of the system to be cleaned, including the determination of cleaning conditions, selection of cleaning agents, recycling design, etc. During the cleaning process, key parameters and conditions (such as time, temperature, conductivity, pH, flow rate, etc.) can be pre-set and monitored.

CIP online cleaning system: (For reference, it can be determined based on the actual situation of the system to be cleaned)

1. Water washing: 10-20 minutes, temperature 40-50 ℃

2. Alkali washing cycle: 20-30 minutes, temperature 60-80 ℃

3. Intermediate water washing cycle: 10 minutes, temperature 40-50 ℃

4. Pickling process: cycle for 10-20 minutes, temperature 60-80 ℃

5. Final water washing process: 15 minutes, temperature 40-50 ℃